Intracytoplasmic Sperm Injection

Intracytoplasmic Sperm Injection

In ICSI, the embryologist selects one normal, motile sperm under high magnification and injects it directly into the egg cytoplasm with a fine needle — helping couples whose eggs and sperm cannot fertilize on their own.

CHAPTER 01

Intracytoplasmic Sperm Injection (ICSI)

ICSI is an advanced IVF technique in which one normal-looking, motile sperm is selected under a microscope and injected directly into the egg cytoplasm.

It can be used when sperm count or motility is too low for sperm to penetrate the egg and complete fertilization on their own.

Indications
  • Severe male-factor infertility that prevents the sperm and egg from fertilizing.
  • Non-male-factor infertility in which conventional IVF cannot achieve fertilization.
  • Use of frozen-thawed eggs.
  • Use of in-vitro matured eggs.
  • Preimplantation genetic testing or diagnosis (PGT-A / PGT-M), to prevent sperm outside the embryo from affecting the accuracy of the embryo sample.
CHAPTER 02

Process

01

Egg + sperm retrieval

Eggs and sperm are prepared on the same day.

02

Sperm selection

The best sperm is selected under the microscope.

03

Microinjection

A fine needle injects the sperm into the egg.

04

Fertilization check

The fertilization status is observed.

CHAPTER 03

IVF vs. ICSI

ComparisonConventional IVFICSI
FertilizationEggs and sperm co-cultured for natural fertilizationA single sperm injected manually
Sperm neededHundreds of thousandsOne per egg
Best forRoughly normal semenMale factor / planned PGT
Fertilization rate50–70%70–80%
CHAPTER 04

FAQ

QCan ICSI damage the egg?

ICSI is an invasive procedure, but having it performed by a skilled embryologist can reduce the risk.

QCan frozen sperm be used for ICSI?

Yes. Suitable sperm only need to be selected from the sample.

QDoes ICSI affect embryo development?

Since ICSI was introduced, the risk of damage to eggs has been low, and its effect on embryo development has also been limited.

Precision meets life.

Give every egg a chance to fertilize

BRC evaluates whether ICSI is suitable based on your semen analysis and supports fertilization with precise microinjection.

Intracytoplasmic Sperm Injection (ICSI) | Becoming Reproductive Center | Premier IVF & Comprehensive Fertility Care